oMeds
Biomarker reference
Biomarker · Hormones

Follicle-Stimulating Hormone (FSH)

Also known as: FSH

FSH is the pituitary hormone that drives ovarian follicular development (women) and spermatogenesis (men). Elevated FSH in midlife women signals declining ovarian reserve; in men it provides context on testicular function.

Medically reviewed
Dr. Laura Purdy · MD, MBA
Clinical Director, oMeds
Last reviewed
Category Hormones
Units mIU/mL
Abbreviation FSH
Definition

What Follicle-Stimulating Hormone measures

Follicle-stimulating hormone (FSH) is a pituitary gonadotropin that drives ovarian follicle development in women and Sertoli cell function (spermatogenesis) in men.

Why It Matters

Clinical significance

FSH defines reproductive stage in women (perimenopause, menopause) and characterizes male hypogonadism as primary (testicular failure, high FSH) or secondary (pituitary, low/normal FSH).

oMeds interpretation

How oMeds reviews it

Required when characterizing hypogonadism and in perimenopause assessment. Provider review pairs FSH with LH, estradiol, and (in men) total testosterone.

Reference Range

Standard clinical reference intervals

Lab-reported reference ranges from established standards bodies. These are diagnostic thresholds — they do not represent optimization targets.

Adult male · Reference
1.5–12.4 mIU/mL

Source: LabCorp adult male reference

Adult female · Reference
1.5–12 mIU/mL

Source: Reproductive-age follicular phase reference

FAQ

Follicle-Stimulating Hormone — frequently asked

What FSH indicates menopause?

Persistent FSH >25 mIU/mL with absent menses for 12 months supports menopause diagnosis.

Provider-reviewedLaura Purdy, MD, MBA · Clinical Director, oMedsReviewed Revr1-2026-06-02 (Jun 2, 2026)
Citations

Source literature

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