Hypothyroidism
Also known as: Underactive Thyroid
Hypothyroidism is under-production of thyroid hormone, most commonly from autoimmune destruction. It presents with fatigue, cold intolerance, weight gain, and constipation.
What you need to know
Hypothyroidism is diagnosed by elevated TSH with low free T4 (overt) or normal free T4 (subclinical). The dominant cause in adults is Hashimoto's thyroiditis. Provider-reviewed care interprets TSH alongside free T4, free T3, reverse T3, and TPO antibodies, never on TSH alone. Replacement decisions weigh symptoms, biomarker trajectory, and individual context.
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