What is prediabetes?
Prediabetes is a state of impaired glucose regulation — A1C 5.7–6.4%, fasting glucose 100–125 mg/dL, or impaired glucose tolerance — that precedes type 2 diabetes.
Full answer
Prediabetes is identified by A1C of 5.7 to 6.4 percent, fasting glucose of 100 to 125 mg/dL, or 2-hour glucose on OGTT of 140 to 199 mg/dL. It represents a meaningful inflection point: progression to type 2 diabetes is common but not inevitable, and the trajectory is responsive to nutrition, sleep, training, and weight modification. Within oMeds review, prediabetes is interpreted alongside fasting insulin, HOMA-IR, triglycerides, and HDL — the broader insulin-resistance pattern — rather than as an isolated glucose finding. Pathway emphasis is on durable insulin-sensitivity improvement.
Educational. Not a substitute for individualized provider review.
- Metabolic Optimization pathway — Primary source · oMeds
- Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29