oMeds
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Answer · longevity

What is NAD+ IV therapy?

Short answer

NAD+ IV therapy delivers nicotinamide adenine dinucleotide intravenously to raise cellular NAD+ levels, which decline with age and metabolic stress.

Reviewed by Dr. Laura PurdyMay 29, 2026

Full answer

NAD+ is an essential cofactor for energy metabolism, DNA repair, and sirtuin signaling. Levels decline with age and rise transiently with NAD+ or precursor (NR, NMN) administration. IV NAD+ achieves higher acute exposure than oral precursors. Within oMeds review, NAD+ therapy is positioned within longevity and recovery pathways under provider direction, with patient counseling on the still-evolving outcome evidence and the gap between mechanistic plausibility and durable clinical endpoints.

Educational. Not a substitute for individualized provider review.

References & sources
  • NAD+ pathway — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29
Primary source
NAD+ pathway