What is PCOS?
Polycystic ovary syndrome (PCOS) is a common hormonal condition in women characterized by androgen excess, ovulatory dysfunction, and frequently insulin resistance.
Full answer
PCOS is diagnosed by two of three Rotterdam criteria: oligo-/anovulation, clinical or biochemical hyperandrogenism, and polycystic ovarian morphology on ultrasound. The biomarker signature commonly shows elevated free testosterone, elevated free androgen index, low SHBG, often elevated LH/FSH ratio, and frequently insulin resistance with elevated fasting insulin and HOMA-IR. Within oMeds review, PCOS-pattern biomarkers are interpreted alongside cycle history, symptoms (acne, hirsutism), and metabolic context. Pathway design typically combines metabolic and hormone optimization strategies under provider direction.
Educational. Not a substitute for individualized provider review.
- Free Androgen Index — Primary source · oMeds
- Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29