Sermorelin
Also known as: Growth Hormone Releasing Hormone Analog · GHRH Analog
Sermorelin is a GHRH analog that stimulates the pituitary to release endogenous growth hormone in a pulsatile pattern. It is used in adult growth hormone optimization where appropriate and is distinct from exogenous HGH administration.
Binds pituitary GHRH receptors to stimulate endogenous pulsatile growth hormone release, preserving physiologic feedback control.
What you need to know
Sermorelin is a synthetic analog of the first 29 amino acids of GHRH. Unlike exogenous HGH, sermorelin preserves the body's natural feedback loops and pulsatile release pattern, which is considered closer to physiologic. Adult use is provider-reviewed and typically targets recovery, body composition, and sleep architecture in the context of broader optimization. IGF-1 is the principal monitoring biomarker.
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