oMeds
All comparisons
Comparison · hormone optimization

TSH vs Full Thyroid Panel

TSH alone is the screening standard but misses central hypothyroidism, conversion defects, and autoimmune thyroiditis. A full panel (TSH, Free T4, Free T3, Reverse T3, TPO/Tg antibodies) is required when symptoms persist despite a normal TSH.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
TSH alone
Full thyroid panel
Markers included
TSH only
TSH, Free T4, Free T3, Reverse T3, TPO, Tg antibodies
Catches conversion defects
No
Yes
Catches autoimmune thyroiditis
No
Yes
Catches central hypothyroidism
No
Yes
Use case
Screening
Symptomatic patient, optimization
Choose TSH alone

TSH alone is sufficient when asymptomatic and no prior thyroid history.

Choose Full thyroid panel

Full thyroid panel is decisive when symptoms suggest thyroid dysfunction, when TSH is borderline, or during hormonal optimization.

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

If my TSH is normal, am I done?

Not when symptoms persist — TSH-only misses conversion and autoimmune defects.

Is the full panel on the standard panel?

TSH and Free T4 are standard; Free T3, Reverse T3, and antibodies are added during thyroid-anchored optimization.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

Begin assessment