Tadalafil vs Vardenafil
Tadalafil is a long-acting PDE5 inhibitor (~36 hour window) available as on-demand or daily-low-dose therapy. Vardenafil is a short-acting PDE5 inhibitor (~4–6 hour window). Tadalafil is the modern default for most ED candidates due to spontaneity and daily-dosing flexibility.
Tadalafil is the modern default — either on-demand or as daily low-dose therapy — for most ED candidates.
Vardenafil is reserved for select cases of intolerance to other PDE5s and is not in the oMeds formulary.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Why is tadalafil preferred?
Longer window, daily-dosing option, and minimal food effect support broader candidacy.
Can vardenafil be combined with TRT?
PDE5 selection is provider-reviewed alongside testosterone optimization candidacy and cardiovascular context.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
Begin assessment