Sermorelin vs TRT
Sermorelin and TRT target different axes. Sermorelin signals the pituitary to release growth hormone in physiologic pulses, supporting sleep architecture, recovery, and body composition. TRT addresses the gonadal axis directly. They are not interchangeable — and in select cases they are paired under provider review.
Sermorelin is appropriate when the clinical case is recovery, sleep architecture, or body composition in a candidate with documented GH-axis decline.
Explore pathwayTRT is appropriate when biomarkers and symptoms confirm gonadal-axis testosterone deficiency.
Explore pathwayEducational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Can sermorelin and TRT be paired?
In select cases, under provider review. They are not automatically combined and are never stacked by patient preference alone.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
Begin assessment