Progesterone vs Progestin
Micronized progesterone is bioidentical to endogenous progesterone and is the modern default for endometrial protection in BHRT. Synthetic progestins (e.g. medroxyprogesterone) are structurally distinct molecules with different receptor and breast-tissue signaling.
Bioidentical micronized progesterone is the modern default for endometrial protection and sleep support in BHRT candidates.
Explore pathwaySynthetic progestins are legacy therapy outside the oMeds BHRT pathway.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Is bioidentical progesterone always better?
It is the contemporary default for most candidates due to favorable safety signal, but candidacy is provider-reviewed individually.
Does progesterone help sleep?
Its allopregnanolone metabolite has GABAergic activity that supports sleep onset for many women.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
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