oMeds
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Comparison · longevity

NAD+ IV Protocol vs Oral NMN

NAD+ IV delivers direct, high-magnitude tissue replenishment on a periodic cadence. Oral NMN raises NAD+ precursor levels daily at lower magnitude with better convenience. The two are complementary in modern longevity protocols.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
NAD+ IV protocol
Oral NMN
Bioavailability
Direct, high
Precursor pathway
Cadence
Periodic infusions
Daily oral
Magnitude per dose
Large
Moderate
Convenience
Clinic visit required
At-home
Cost per cycle
Higher
Lower
Choose NAD+ IV protocol

NAD+ IV is the provider-reviewed pathway when high-magnitude periodic replenishment is the goal.

Explore pathway
Choose Oral NMN

Oral NMN is appropriate as daily background support and can complement periodic IV protocols.

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

Are they redundant?

No — pulsed IV and continuous oral occupy different roles.

Which has more evidence?

IV evidence is stronger for tissue NAD+ restoration; oral NMN evidence is emerging.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

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