Micronized Progesterone vs Medroxyprogesterone
Micronized progesterone is bioidentical; MPA is a synthetic progestin used in legacy HRT regimens. Modern BHRT favors micronized progesterone for endometrial protection due to a more favorable safety and quality-of-life signal.
Micronized progesterone is the modern default in BHRT for endometrial protection and sleep support.
Explore pathwayMPA is reserved for legacy regimens and is outside the oMeds BHRT pathway.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Why did the WHI signal involve MPA?
The combined-arm signal involved CEE + MPA specifically; bioidentical regimens have a different safety profile.
Can patients switch from MPA to micronized progesterone?
Switching is provider-reviewed against current regimen, uterus status, and symptom profile.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
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