oMeds
All comparisons
Comparison · hormone optimization

Finasteride vs Minoxidil

Finasteride blocks 5-alpha reductase, reducing scalp DHT — the upstream driver of androgenetic alopecia. Minoxidil is a vasodilator that prolongs the anagen (growth) phase. They address different mechanisms and are most commonly used together. Topical formulations reduce systemic exposure relative to oral.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
Finasteride (topical or oral)
Minoxidil (topical or oral)
Mechanism
5-alpha reductase inhibitor — reduces scalp DHT
Vasodilator — prolongs anagen phase
Driver targeted
Upstream hormonal driver
Follicular growth phase
Evidence base
Robust for androgenetic alopecia
Robust for androgenetic alopecia
Side-effect signal (oral)
Libido/mood signal possible — individually reviewed
Cardiovascular signal at oral doses — provider-tuned
Topical exposure
Topical reduces systemic finasteride exposure
Topical is the conventional default
Combination use
Frequently paired with minoxidil
Frequently paired with finasteride
Pathway
oMeds topical pathway
oMeds topical pathway
Choose Finasteride (topical or oral)

Finasteride is appropriate when the goal is to address the upstream hormonal driver of androgenetic alopecia, particularly in TRT-context candidates with scalp-hair concerns.

Choose Minoxidil (topical or oral)

Minoxidil is appropriate when the goal is to extend the follicular growth phase, and is frequently combined with finasteride in provider-reviewed pathways.

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

Can they be used together?

Yes — combination is standard. The oMeds topical pathway is designed around this layering under provider review.

Does TRT require finasteride?

No. Only candidates with androgenetic predisposition need DHT-aware adjuncts. The hair-loss conversation is part of TRT candidacy review.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

Begin assessment