oMeds
All comparisons
Comparison · longevity

Finasteride vs Dutasteride

Finasteride and dutasteride are 5α-reductase inhibitors that reduce DHT. Finasteride inhibits type II 5α-reductase; dutasteride inhibits both type I and II, producing more profound DHT suppression. Finasteride is the modern default for androgenetic alopecia; dutasteride is reserved for select cases.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
Finasteride
Dutasteride
Isoform target
Type II 5α-reductase
Type I + II 5α-reductase
DHT suppression
~70%
~90%
Half-life
~6 hours
~5 weeks
FDA indication for AGA
Yes
Off-label in US (approved in some markets)
Side-effect signal
Recognized libido/mood signal — provider-reviewed
Similar profile; longer washout
Pathway
Hair (topical or oral)
Not offered by oMeds
Choose Finasteride

Finasteride is the modern default for androgenetic alopecia, available in topical and oral formulations under provider review.

Choose Dutasteride

Dutasteride is reserved for select cases where finasteride response is insufficient and is not currently in the oMeds formulary.

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

Is dutasteride more effective?

It produces greater DHT suppression on average; clinical hair-density outcomes are similar in most candidates.

Can topical finasteride reduce side effects?

Topical formulations reduce systemic exposure — that is a provider-reviewed conversation at consult.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

Begin assessment