Estradiol vs Conjugated Estrogens
Estradiol is the bioidentical estrogen used in modern BHRT, available transdermally and orally. Conjugated equine estrogens (CEE) are a mixture of equine-derived estrogens historically used in synthetic HRT. Contemporary provider-reviewed care favors bioidentical transdermal estradiol where clinically appropriate.
Bioidentical estradiol — transdermal where clinically appropriate — is the modern standard in BHRT.
Explore pathwayConjugated estrogens are legacy therapy and not part of the oMeds BHRT pathway.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Are bioidentical hormones safer?
Transdermal estradiol has a favorable cardiovascular and thrombotic profile compared with oral CEE, but every candidacy is provider-reviewed.
Why is transdermal preferred?
It bypasses first-pass hepatic metabolism, reducing VTE risk and lipid disturbance.
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The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
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