Enclomiphene vs hCG
Enclomiphene and hCG both support endogenous testosterone and fertility, but through different mechanisms. Enclomiphene acts at the hypothalamus to raise LH/FSH; hCG mimics LH directly at the testes. Both are provider-reviewed for fertility-preserving optimization, with different candidacy.
Enclomiphene is appropriate when fertility preservation and oral administration are priorities, and the HPG axis is restorable.
Explore pathwayhCG is appropriate for direct testicular stimulation in select TRT-adjunct or fertility-preservation contexts and is not currently in the oMeds formulary.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Can they be combined?
In some provider-reviewed protocols, yes — combination is individualized and is not part of the current oMeds pathway.
Which raises testosterone faster?
hCG produces a more rapid testicular response; enclomiphene response unfolds over 4–8 weeks.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
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