DHEA-S vs AM Cortisol
DHEA-S reflects chronic, slow-pool adrenal output. AM cortisol reflects acute, diurnal-peak adrenal output. The cortisol-to-DHEA ratio captures stress-axis imbalance better than either alone.
DHEA-S is decisive for chronic adrenal reserve, age-related decline, and longitudinal stress trend.
AM cortisol is decisive for diurnal axis status — must be drawn at the morning peak.
Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.
Frequently asked
Can a single cortisol replace a diurnal pattern?
No — for adrenal dysfunction the 4-point diurnal cortisol pattern is preferred.
Is DHEA-S the same as DHEA?
DHEA-S is the sulfated, longer-half-life form and is the standard reference marker.
Take the optimization assessment.
The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.
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