oMeds
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Comparison · hormone optimization

Cyclic vs Continuous Progesterone

Cyclic dosing mimics the natural luteal phase and produces predictable bleeding — preferred in perimenopause. Continuous dosing produces amenorrhea over time and is preferred in postmenopause.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
Cyclic progesterone
Continuous progesterone
Bleeding pattern
Scheduled monthly bleed
Amenorrhea after 6–12 months
Best phase
Perimenopause
Postmenopause
Endometrial protection
Adequate when properly dosed
Adequate when properly dosed
Side-effect profile
Cyclic mood/sleep variation
Steadier symptom control
Cadence
Days 1–14 or 14–28 typically
Nightly
Choose Cyclic progesterone

Cyclic progesterone is the provider-reviewed default in perimenopause where ovarian activity persists.

Explore pathway
Choose Continuous progesterone

Continuous progesterone is the provider-reviewed default in postmenopause to achieve amenorrhea and steady symptom control.

Explore pathway

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

Will I still bleed on continuous?

Spotting can occur in the first 6–12 months, then typically resolves.

Can I switch?

Yes — provider review reassesses as phase progresses.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

Begin assessment