oMeds
All comparisons
Comparison · longevity

CRP vs hs-CRP

Standard CRP detects acute, large-magnitude inflammation. hs-CRP detects the low-grade chronic inflammation that drives cardiovascular and metabolic disease. For optimization, hs-CRP is the relevant marker.

Reviewed by Dr. Laura PurdyMay 29, 2026
Attribute
Standard CRP
hs-CRP
Detection range
High inflammation
Low-grade chronic
Use case
Acute illness, infection
CV risk, metabolic optimization
Decisional weight
Acute care
Longitudinal optimization
On standard panel
Sometimes
Yes — during optimization
Trend value
Low
High
Choose Standard CRP

Standard CRP is decisive when acute infection or illness is suspected.

Choose hs-CRP

hs-CRP is the optimization marker — read longitudinally for cardiovascular and metabolic trend.

Educational. Final pathway selection is provider-reviewed via synchronous video consultation against your biomarkers, history, and goals.

Frequently asked

Are they the same test with different sensitivity?

Yes — hs-CRP uses a more sensitive assay to detect lower concentrations.

What raises hs-CRP transiently?

Recent infection or injury can transiently raise hs-CRP — provider review interprets context.

Next step

Take the optimization assessment.

The adaptive assessment maps your symptoms, history, and goals to candidate pathways — and routes you into provider review.

Begin assessment