oMeds
All answers
Answer · longevity

Which pathway addresses prolonged post-workout soreness?

Short answer

Prolonged DOMS reflects recovery capacity. Candidates with documented GH-axis decline → sermorelin. Cellular-decline patterns → NAD+. Men with confirmed low testosterone → TRT. Sleep, protein, and deload weeks remain foundational.

Reviewed by Dr. Laura PurdyMay 29, 2026

Full answer

Recovery is downstream of sleep, protein, training load periodization, and hormonal context. Provider review screens these inputs first. Candidates with documented age-related GH decline whose primary signal is connective-tissue recovery may be evaluated for sermorelin. Patients with longevity-axis goals and cellular-decline patterns may be evaluated for NAD+. Men with confirmed low testosterone whose recovery improves with optimization may be evaluated for TRT. Every route is synchronous-video reviewed.

Educational. Not a substitute for individualized provider review.

References & sources
  • Sermorelin pathway — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29
Primary source
Sermorelin pathway