oMeds
All answers
Answer · hormone optimization

Which pathway addresses irritability?

Short answer

Irritability is screened for sleep, caffeine, and thyroid first. Peri/menopausal women with matching biomarkers → BHRT. Men with confirmed low testosterone whose irritability tracks with the deficit → TRT.

Reviewed by Dr. Laura PurdyMay 29, 2026

Full answer

Irritability is multifactorial. Provider review screens sleep, caffeine, and thyroid first. Peri/menopausal women with progesterone-pattern irritability and matching biomarkers are evaluated for BHRT. Men with confirmed low testosterone whose irritability improves with optimization are evaluated for TRT. Every initiation requires the standardized biomarker panel and synchronous video review.

Educational. Not a substitute for individualized provider review.

References & sources
  • Bhrt Optimization pathway — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29