oMeds
All answers
Answer · longevity

Which pathway addresses chronic inflammation?

Short answer

Chronic inflammation is routed by driver. Visceral adiposity and insulin resistance → metabolic pathways (GLP-1). Cellular-decline inflammaging → NAD+. Lifestyle, omega-3, and sleep are foundational.

Reviewed by Dr. Laura PurdyMay 29, 2026

Full answer

Chronic low-grade inflammation (elevated hs-CRP, ferritin in the absence of iron overload, fibrinogen) is read against the metabolic and longevity axes. The most common reversible driver is visceral adiposity with insulin resistance — BMI-eligible candidates are routed to GLP-1 pathways. Patients with cellular-decline patterns and longevity goals are evaluated for NAD+. Omega-3 status, sleep, and resistance training are foundational. Persistent unexplained inflammation triggers further provider workup rather than pathway escalation.

Educational. Not a substitute for individualized provider review.

References & sources
  • Nad Plus pathway — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-05-29
Primary source
Nad Plus pathway