What is NT-proBNP?

Full answer

NT-proBNP is the inactive N-terminal fragment of pro-B-type natriuretic peptide. It is released from cardiac ventricles when wall stress rises and has high negative predictive value for heart failure in non-acute settings. Age, renal function, atrial fibrillation, and pulmonary hypertension influence interpretation. NT-proBNP is not part of routine wellness panels; it is reviewed when symptoms suggest cardiac dysfunction or to monitor known heart failure.

Educational. Not a substitute for individualized provider review.