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Answer · biomarkers

My triglycerides are high — what should I do?

Short answer

Elevated triglycerides reflect insulin resistance, alcohol, refined-carbohydrate intake, and (rarely) familial dyslipidemia. Address the metabolic driver. Severe elevation (>500 mg/dL) raises pancreatitis risk and warrants prompt review.

Reviewed by Dr. Laura PurdyJune 3, 2026

Full answer

Triglycerides above 150 mg/dL track with insulin resistance; values above 500 mg/dL meaningfully raise pancreatitis risk. The workup includes fasting glucose, fasting insulin, HbA1c, TSH, ALT/AST, alcohol history, and medication review. Refined carbohydrate reduction, weight optimization, alcohol restriction, and aerobic training are first-line. Omega-3 (EPA/DHA) and fibrates are added under provider review when very high. Severe elevation is treated promptly. The metabolic pathway integrates these decisions with the broader baseline.

Educational. Not a substitute for individualized provider review.

References & sources
  • Methodology — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-06-03
Primary source
Methodology