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Answer · biomarkers

My fasting glucose is high — what should I do?

Short answer

Elevated fasting glucose is reconfirmed and paired with HbA1c, fasting insulin, and a lipid panel. Lifestyle is first-line; metformin or GLP-1 receptor agonists are provider-reviewed when warranted by risk and trajectory.

Reviewed by Dr. Laura PurdyJune 3, 2026

Full answer

A fasting glucose in the impaired (100–125 mg/dL) or diabetic (≥126 mg/dL) range is reconfirmed and paired with HbA1c, fasting insulin, HOMA-IR, lipids, and weight/waist. Lifestyle change — nutrition, training, sleep, weight optimization — is first-line. Metformin is considered for prediabetes with progression risk; GLP-1 receptor agonists are reviewed against weight, cardiometabolic risk, and patient goals. Decisions are integrated into the metabolic pathway with the broader baseline rather than treated in isolation.

Educational. Not a substitute for individualized provider review.

References & sources
  • Methodology — Primary source · oMeds
  • Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-06-03
Primary source
Methodology