oMeds
All answers
Answer · hormone optimization

Which pathway addresses chronic fatigue?

Short answer

Fatigue is screened against sleep, thyroid, iron, B12, vitamin D, glucose, and mood. Confirmed deficits are repleted. Confirmed low testosterone routes to TRT; peri/menopausal patterns to BHRT; longevity-axis candidates to NAD+.

Reviewed by Dr. Laura PurdyJune 3, 2026

Full answer

Fatigue is the most common reason patients seek optimization care. The screen pairs sleep history (with apnea risk), TSH/free T4, ferritin and iron studies, B12, vitamin D, fasting glucose, HbA1c, hs-CRP, and mood. Confirmed deficits are repleted first because hormone optimization cannot substitute for reversible drivers. Men with confirmed low testosterone are evaluated for TRT. Peri/menopausal women are evaluated for BHRT. Patients prioritizing cellular and longevity-axis goals can add NAD+. Every plan is synchronous-video reviewed.

Educational. Not a substitute for individualized provider review.

References & sources

Related pathways

All pathways →
Pathway
TRT
A provider-reviewed pathway designed to explore testosterone, recovery, hormonal wellness, and longitudinal performance — built around your biomarkers, not assumptions.
Explore
Pathway
BHRT
A bioidentical, provider-reviewed pathway designed to support hormonal balance, recovery, sleep, and longitudinal wellbeing — informed by biomarkers, not guesswork.
Explore
Pathway
NAD+
NAD+ supports the cellular systems behind how you feel, train, think, and recover — delivered to your door.
Explore
Pathway
Vitamin B12
A B12 pathway designed to support cellular energy, methylation, and metabolic resilience — reviewed against your biomarkers, not assumed by symptoms.
Explore
Primary source
Testosterone Optimization pathway