What disqualifies someone from BHRT?
Active estrogen-sensitive cancer, recent venous thromboembolism, active hepatic disease, undiagnosed vaginal bleeding, and selected cardiovascular contexts. Provider review integrates personal and family history.
Full answer
Absolute contraindications to BHRT include active estrogen-sensitive cancer (breast, endometrial), recent venous thromboembolism or active thromboembolic disease, active hepatic disease, undiagnosed vaginal bleeding, and a history of estrogen-sensitive cancer in selected cases. Relative contraindications and decision points include strong family breast cancer history, migraine with aura, uncontrolled hypertension, and selected cardiovascular contexts. Modality (transdermal favored for thrombotic risk) and timing of initiation relative to menopause onset are part of the candidacy discussion. Every decision is synchronous-video reviewed.
Educational. Not a substitute for individualized provider review.
- BHRT Optimization pathway — Primary source · oMeds
- Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-06-03

