Am I a candidate for tadalafil or sildenafil?
PDE5 inhibitors are appropriate for vascular-pattern erectile changes in men with acceptable cardiovascular candidacy and no nitrate use. Provider review confirms candidacy and selects molecule, dose, and frequency.
Full answer
Tadalafil and sildenafil are PDE5 inhibitors used for erectile changes with a vascular pattern. Candidacy requires no concurrent nitrate or guanylate cyclase stimulator use, acceptable cardiovascular candidacy (no recent MI, unstable angina, severe hypotension), and absence of severe hepatic dysfunction. Drug interactions with alpha-blockers and certain antihypertensives are reviewed. Provider review selects molecule and dosing pattern (on-demand vs daily low-dose tadalafil). Cardiovascular workup is referred when warranted independent of PDE5 therapy.
Educational. Not a substitute for individualized provider review.
- Sexual Wellness pathway — Primary source · oMeds
- Reviewed by Dr. Laura Purdy, MD, MBA · Clinical Director, oMeds · Last reviewed 2026-06-03